Step-up therapy with biphasic insulin aspart-70/30—Sapporo 1-2-3 study

Step-up therapy with biphasic insulin aspart-70/30--Sapporo 1-2-3 study.

The effectiveness of BIAsp 30 step-up therapy in achieving glycemic control in Japanese patients with type 2 diabetes mellitus was investigated. Study subjects were 99 patients with type 2 diabetes mellitus aged over 20 years who were judged to require insulin therapy due to poor glucose control (HbA1c level of > or =7.5%). BIAsp 30 dosage was determined by the patient's attending physician; co...

Step - up therapy with biphasic insulin aspart - 70 / 30

DMSOTT-3408-biphasic insulin aspart

Correspondence: P Valensi Service d’endocrinologie-DiabétologieNutrition, Hôpital Jean Verdier, Avenue du 14 Juillet, 93143, Bondy Cedex, France Tel +33 1 48 02 65 97 Fax +33 1 48 02 63 56 email [email protected] Abstract: The pharmacological advantages of the rapid-acting analog, insulin aspart, over human insulin have contributed to the widespread prescription of the premix, biphasic i...

Immune responses to insulin aspart and biphasic insulin aspart in people with type 1 and type 2 diabetes.

OBJECTIVE The antibody responses to a novel rapid-acting insulin analog, insulin aspart (IAsp), and their potential clinical correlates were studied with a specifically developed method in 2,420 people with diabetes treated for up to 1 year with preprandial subcutaneous injections of IAsp. RESEARCH DESIGN AND METHODS Circulating insulin antibodies were analyzed by radioimmunoassay with (125)I...

Biphasic Insulin Aspart 30: Premix Analogue for Initiating Insulin Therapy in Type 2 Diabetes

Introduction T he last two decades have seen an explosive increase in the number of people with diabetes globally due to changes in lifestyle and genetic predisposition 1,2 Patients with diabetes mellitus have an impaired capacity to regulate blood glucose. In type 1 diabetes, autoimmune destruction of pancreatic beta cells results in a diminished and rapidly absent ability to produce insulin. ...